Coronary Diseases

Diagnosis and its methods of COVID

The Coronavirus Disease 2019 (COVID‑19) pandemic has forced the scientific community to rapidly develop highly reliable diagnostic methods in order to diagnose this pathology effectively and accurately, thus limiting the spread of infection. Although the structural and molecular characteristics of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) were initially unknown, various diagnostic strategies useful for making a correct diagnosis of COVID‑19 have been rapidly developed by private research laboratories and biomedical companies. At present, rapid antigen or antibody tests, immunoenzymatically serological tests and molecular tests based on RT‑PCR are the most widely used and validated techniques worldwide. Apart from these conventional methods, other techniques, including isothermal nucleic acid amplification techniques, clusters of regularly interspaced short palindromic repeats/Cas (CRISPR/Cas) ‘based approaches. RT-PCR-based molecular test

• Rapid antigen and rapid antibody tests
• Immunoenzymatically serological test
• Viral culture and electron microscopy
• NGS
• Clinical investigations and imaging techniques
• Biosensor COVID-19 testing techniques
• Loop-mediated isothermal amplification (LAMP) COVID-19 testing methods
• CRISPR/Cas-based COVID-19 testing methods
• Digital PCR COVID-19 testing methods